Friday, May 22, 2020

An Examination of the Machine Gun - 920 Words

Weapons of war are useful in killing human lives and causing widespread destruction and terror. The machine gun is such a weapon that has allowed for the mass extinction of those on the receiving end of its power. The purpose of this essay is to examine the machine gun in a historic perspective in order to contextualize its practicality and importance in modern history. This examination will describe the development, the current impact and the future of this tool of war in order to reveal the importance of their presence. The development of means to extinguish human existence usually arrives out of necessity. Cantrell (2012) described the birth of the machine gun by Richard Gatling as a quantum development in the evolution of firearms. Ironically, Cantrell supposed that Gatling created a weapon so devastating and superior in its firepower that opposing armies would have no chance of victory. While Gatlings intentions seemed well placed, it seems that this idea perhaps has backfired . The machine gun was introduced in the American Civil War around the year 1862 in order to serve as a deterrent for weaker forces to attack. Firepower was concentrated in this tool so that one person operating a Gatling machine gun would replace many men on the battlefield. Essentially this invention permitted for more casualties occurring at a more rapid pace. The early version of this gun had 5 to 10 barrels arranged in a cylinder revolved by turning a hand crank. It was made inShow MoreRelated Yojimbo : Ideology and Interpretation Essay1180 Words   |  5 Pagesthe conflict of man versus machine. The weapon used by the samurai is his sword, which requires an element of skill and entails an entire individual set of ideologies. The brother of one of the gang leaders appears with a gun for the majority of the film. The gun, as a product of man, represents the absence of all of the ideologies that a samurai embodies. The utilization of a gun eclipses the man using it, and man becomes subordinate to the dexterity of the gun. Aside from this, drawing theRead MoreHow Did the Development of Technology Affect World War 1?1358 Words   |  6 PagesTechnology greatly affected the way in which wars were fought, especially in World War I. The inventions of the repeating machine gun, the development of poison gas, and the introduction of the first tanks caused armies to fight using the bunkering method. This allowed men to huddle in trenches along what are called skirmish lines and throw, lob, and fire by other means weapons to cause damage while men were protected by about 4 to 5 feet deep earth. This caused men to fight in rear or echelon columnsRead MorePublic Gun Control And The United States1732 Words   |  7 PagesPublic Gun Control in the United States Gun Control in the United States of America is a sensitive (understatement) topic that has resulted in various criticism and support by many citizens of the United States (also an understatement). Some citizens believe that the guns don t kill people; it is the people that kill people while others believe that guns lead to violence and a feeling of control and power over others. The belief of some is that if firearms were to be eliminated from the publicRead MoreThe s Instructions Jumping Off The Examination Bed931 Words   |  4 PagesApril had perked up at Darp’s instructions, jumping off the examination bed. Carrie stood up and squeezed April’s hand, the atmosphere had lightened after Darp’s instructions. Rick felt calmer now that Darp had taken charge. He had never wanted the responsibility of balancing his dealing with the aliens and humanity. Rick’s easy going and simple life had been totally upset when Darp had insisted he acted as an arbitrator to the treaty. The Executive Committee of the United Government had reluctantlyRead MoreImpact Of Ballistics On Forensics Science And How It Helped Advance The Field1240 Words   |  5 Pagesof a crime. It is used to answer crucial questions at a crime screen such as, how the gun was used, what was the reason they used it and how frequently has the gun been used to practice the action of a crime. There are three sub fields of ballistics that are used to gain the knowledge necessary to answer the questions previously stated. Each field is a study that focuses on three different stages of when a gun has been fired. The first stage is called internal ballistics. This stage more so examinesRead MoreTIG Welding Essay example1469 Words   |  6 Pages• www.welding.com b. Equipments and Materials b.1. Equipments • Welding Machines • Power Supply • Welding Gun (Torch) • Water Cooling System • Shielding Gas Tube • Pressure control and measurement systems for inert gas • Tensile Testing Machine • Bending Test Machine • Hardness Measurement Device • Furnace for Heat Treatment • Charpy Impact Test Machine • Microscopes for Metallographic Examinations b.2. Materials • Stainless Steel work pieces of different types • TungstenRead MoreGun Control Informative Essay1424 Words   |  6 PagesInformative essay The United States is in a controversy of whether or not the Second Amendment is protecting our country or killing it. The United States owns approximately 250 million guns, nearly one for each citizen, and grows about 7 million each year. Experts believe that the Second Amendment in the Constitution is rational and legal, author of, Handgun Prohibition and the Original Meaning of the Second Amendment Don B. Kates states that the â€Å"Second Amendment protects an individuals rightRead MoreThe Horizon s Setting 2020 Strategy1732 Words   |  7 PagesAbstract: The term dependable (examination and) advancement has increased expanding EU arrangement significance in the most recent two years, specifically inside of the European Commission s Science in Society program, in the Horizon s setting 2020 Strategy. We give a brief verifiable diagram of the idea, and distinguish three particular components that are rising up out of related talks. The principal is an accentuation on the equitable administration of the reasons of exploration and advancementRead MoreThe Dark Story of Babi Yar1095 Words   |  4 Pagesreunited with their things when they reached their final destination. Before they knew it, they were surrounded by soldiers with huge machine guns and ferocious. Then they were taken in small groups and told to go to the edge of the ravine and undress. Afterwards they had to go into the ravine and lay down (Public Broadcasting System). The soldiers with the machine guns went around and shot the people who had just lain down. They would repeat this process many times, and continue to shot the remainingRead MorePlasma Spray Coatinging Case Study913 Words   |  4 PagesïÆ'Ëœ Distances between nozzle of the plasma spray gun and surface has to 100mm to 150mm. G. The importance of the study By the end of the proposed project work we can achieve the market demand for the cheap and efficient feedstock material for plasma spray coating. Because fly-ash mechanical properties will boost both mechanical and thermal substrate properties. And also improve the durability of the metallic substrate due to improved wear resistances of the substrate. Cost of the feedstock material

Thursday, May 7, 2020

What Is The Alternative Lengthening Of Telomeres - 900 Words

DNA replication results in the gradual shortening of telomeres over time, leading to the activation of senescence or apoptosis. Therefore, telomere length is a key biological signal to limit the indefinite proliferation of somatic cells (Roumelioti, et al., 2016). However, cancer cells can overcome telomere shortening by synthesising a new telomeric DNA from an RNA template through the expression of telomerase (Roumelioti, et al., 2016). Alternatively, 10-15% of human cancers utilise a DNA template in a homology-directed synthesis mechanism called alternative lengthening of telomeres (ALT) (Cesare Reddel, 2010). However, the process by which DNA damage such as telomeric shortening results in the execution of homology-directed synthesis,†¦show more content†¦However, ATR, Rad51 and Hop2 were not required for break-induced telomere synthesis in ALT cells and in fact, knockdown of each gene increased the levels of nascent telomeres. To further support their findings, Dilley an d colleagues studied VA13 HOP2 CRISPR clones lacking Hop2 protein expression and found that no telomere shortening took place. From these findings, the authors could therefore propose that break-induced telomere synthesis and ALT telomere maintenance can occur independently of Rad51-Hop2 and ATR. Dilley and co-workers subsequently determined that the replicative DNA polymerase Pol , including POLD3, POLD4 and POLD1 subunits, were instead required for break-induced telomere synthesis. Whereas Pol , Pol -primase and MCM2-7 replicative helicase were found to be nonessential and were recruited at far lower levels. The POLD3 subunit is also part of the Pol ÃŽ ¶ complex involved in translesion synthesis. However, the REV3L catalytic subunit of Pol ÃŽ ¶ was not required for break-induced telomere synthesis, suggesting POLD3 primarily acts through Pol . This major role of POLD3 has been supported in studies that revealed POLD3 depletion resulted in decreased frequency of replicated ALT telomeres (Roumelioti, et al., 2016). Overall, the results by Dilley et al led to the suggestion that an alternative replisome is required for ALT telomere synthesis. Having proven that Pol is dominantly recruited to TRF1-FokI damage sites, Dilley et al set outShow MoreRelatedScientific Literature Focused On Chromosomal Dna And Dna, Blood Leukocytes, Sputum, And Buccal Cells2398 Words   |  10 PagesChromosomal Telomere Length (TL) In Blood Leukocytes, Sputum, and Buccal Cells as It Relates to Cancer Occurrences by: Andy Barajas Bio 490, Fall 2014 Department of Biological Sciences California State Polytechnic University, Pomona Abstract This is a conglomeration of scientific literature as it relates telomere length in blood cells to the occurrence of cancer. Telomeres are composed of repeating TTAGGG nucleotides and they are found at the ends of chromosomes. These chromosomal caps are what protect

Wednesday, May 6, 2020

Life, Liberty, and the Pursuit of Happiness Free Essays

? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 17109201 ? ? ? ? ? ? ? ? ? ? ? ? ? 2012. 1. 5 Life, Liberty, and the Pursuit of Happiness ——A Probe into the Character of Emily A Rose for Emily is a short story written by American author William Faulkner first published in the April 30, 1930 issue of Forum. We will write a custom essay sample on Life, Liberty, and the Pursuit of Happiness or any similar topic only for you Order Now It describes the tragedy of a typical southern lady, Miss Emily, who is deeply victimized in her character and mind by the conventional system of the South and patriarchy; thus even though she wants to fight, she still fails to confront and deal with the changes caused by the shock of northern industrialization all by herself and finally leads to destruction and self-destruction on the way of pursuing happiness. This essay concentrates on exploring the character of Emily with the efforts she has made for her life and especially the reasons for her failure in â€Å"fighting† from the three aspects as Life, Liberty, and the Pursuit of Happiness, (the well-known phrase applied from the United States Declaration of Independence). 1. The Backup of Early Life As a descendent of the southern conventional noble family, Emily was born in the environment full of the thought of feudalism and hierarchy which makes her acquire not only the attitude of arrogance and indifference to common people, but, most importantly, the habit of obedience to her father. Before her father dies, he is the only one Emily could rely on in her family. Therefore, there should be no blame to her that she depended on her father when she was still young, just as most of us would depend on our parents during our childhood and youth. However, the fact the she gets to be thirty and is still single reveals the abnormality of the dependence. Actually, it is no longer pure dependence on her father. Instead, the dependence has developed into over obedience which then is taken advantage of by her father to control her completely under the constraint of the old southern tradition. The control is just described by William Faulkner as the tableau, â€Å"Miss Emily a slender figure in white in the background, her father a spraddled silhouette in the foreground, his back to her and clutching a horsewhip, the two of them framed by the back-flung front door†. The father, a typical symbol of patriarchy, clutching a horsewhip, acts as a tyrant. It’s him who holds the Griersons always a little too high for what they really are and uses his horsewhip, which exactly symbolizes patriarchy, to beat off all of the young men who come to make proposals to his daughter, Miss Emily, believing that no one is quite good enough for her. In fact, in his opinion, none of the young men are quite good enough not for his daughter, but for the old southern tradition and its dignity. He never regards Emily as an independent individual. On the contrary, he regards her as the tool to maintain their dignity in the conventional system. However, Emily has been regarding her father as the whole backup of her life since she was born. What’s more, she has been in this state for more than thirty years. She has long been used to this dependence and even allows this kind of dependence to conquer her strong desire for free life and love. To her, this dependence is just her whole life. Therefore, when her father dies, she cannot accept the fact because her father is her whole dependence and the dependence is just her whole life. Her father’s death has also deprived all the hope of her life. Her father and the old tradition her father represents are the root of Emily’s tragedy; thus, her father’s death should be regarded as the chance for Emily to free herself from the constraint of the conventional system. It’s the beginning of Emily’s fighting for her own life, liberty and happiness. 2. Liberty Getting rid of her father’s control is just like releasing from a prison. After a long time of being sick, she is seen again with hair cut short and looks like a girl, which declares the beginning of her liberty. However, Faulkner describes her as resembling to those angels in colored church windows—sort of tragic and serene. The word of â€Å"tragic† seems to have indicated the sad ending of Emily’s life even though she has the chance to gain liberty. And the reason lies on Emily’s wrong interpretation of liberty. From the description by Faulkner, after her father’s death, the character of Emily appearing before the readers is still such an arrogant and indifferent person typically symbolizing the old tradition. It is clearly known by the readers that actually Emily never frees herself from the fetter of the conventional system even though she has gotten rid of her father’s control. However, Emily sees her liberty from a different angle. To her, liberty means to live in a way she has long been used to at her own will. Since her father died, nobody and nothing can ever take her under control any more. Therefore, she ignores all the others’ denouncing the smell of her house, vanquishes the new generation’s demanding her taxes and rejects the newer generation’s attaching a mailbox. She still carries her head high enough—even when others all believe that she is fallen, because the way of living she has been used to is just to maintain dignity as much as she can in the environment of the old southern tradition. She refuses to free herself from the conventional system because it’s the very place she feels relatively free. In contrast, the new world with all those changes caused by the shock of northern industrialization is where she will feel unsafe, uneasy and uncomfortable. Similarly in the film The Shawshank redemption, the two people, the old log, Brooks, and one of the protagonists, Red, have much difficulty in adjusting themselves to the life outside after they get their parole from decades of imprisonment. Brooks even commits suicide and Red can never pea unless asking for permission. And Emily has also been imprisoned for more than thirty years which has made her long ago assimilated by the old tradition. Emily has made efforts for her life and liberty after her father’s death. Unfortunately, she interprets her liberty in the way which is against the development of the new world both in aterial and spiritual aspects. And her false interpretation is still due to the over thirty years’ imprisonment of patriarchy and the conventional system of the South. 3. The Pursuit of Happiness Even though the living style has been assimilated by the convention, there is still something that everyone is born with including Emily. That is the desire for happiness. Emily lives in her own old world but all alone. She earns liberty but lacks happiness. Therefore, when Homer Barron shows up, she believes that he is the source of her happiness and makes up her mind to grasping the slight of hope. However, the chance of gaining happiness is ruined again by the conflict between her old world and the shock of northern industrialization. What’s worse, finally she leads to the road of destruction and self-destruction by her extreme desire resulting from patriarchy and the old tradition’s severe oppression Homer Barron, a Yankee, comes from the north and symbolizes the northern industrialization, which is definitely against the old tradition and even some basic principles of Emily’s own old world such as the feature of dignity. But on the other side, he seems to Emily the hope for her happiness. As a woman oppressed by spiritual loneliness for such a long time, the desire for love and happiness is strong enough to for Emily to conquer the continual restraint of conventional hierarchical thought. As a result, she goes out of the old house, which symbolizes the convention, with her head high and together with Homer Barron with his hat cocked and a cigar in his teeth, reins and whip in a yellow glove driving in the glittering buggy on Sunday afternoons. She even decides to marry him by buying a complete outfit of men’s clothing regardless of all the objects and conflicts. During this period, she has gradually become deeply trapped in the love and happiness with Homer Barron. She has been oppressed by patriarchy and the southern convention for more than thirty years, and now the love she is experiencing is so unique and incomparable that it has become the whole happiness of her life and that it is impossible for her to let it go. If Homer Barron isn’t going to leave her, then the love and happiness will certainly continue. However, as the symbol of northern industrialization, Homer Barron holds a completely opposite attitude towards the relationship with Miss Emily. He just regards it as a pure way of entertainment without any responsibility, which is a sharp conflict between not only Homer and Emily, but also the morals of northern industrialization and the old southern convention. Under the pressure of the conflicts and the long-term victimization by patriarchy and the convention, Emily’s character and mind has been completely deformed. In the end, to prevent the happiness from disappearing, Emily takes drastic measures as killing Homer and let the body stay with her forever so that her love and happiness will also never leave. This measure finally destroys her whole life and leaves her a complete tragedy as well as Homer Barron. In this extraordinary short story, the character of Emily William Faulkner created has made some efforts to earn her own life and liberty and even persist in the pursuit of happiness. However, her life is based on patriarchy and the conventional system of the South for more than 30 years; the liberty she goes after is still trapped in the old tradition; and her pursuit of happiness comes across the conflicts between the southern old tradition and the shock of northern industrialization. All of these negative factors lead to the final tragic destruction. References Olga W. Vickery. The Novels of William Faulkner: A Critical Appraisal [M]. Baton Rouge: Louisiana State University Press, 1964 Fang Yigui [ ]. [J]. ,2007 1 Liu Aiying [ ]. [J]. ,1998 2 Liu Zhuo [ ] Peng Changliu [ ]. : [J]. ,2004 5 Wang Minqin [ ]. [J]. ,2002 2? ,? 66-69 Xiao Minghan [ ].  ·. : ,1997? How to cite Life, Liberty, and the Pursuit of Happiness, Papers